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Covid-19

Learn about how SAR-COV-2 virus actually infects/attacks a cell.

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COVID-19
How does SAR-COV-2 kill cells?
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In order to understand how my product will treat SAR-COV-2, we must understand how SAR-COV-2 infects and destroys cells. 

 

  1. The S-spike protein on the SAR-COV-2 virus binds to the ACE-2 receptor on a cell.

  2. Once bound it allows for the virus to be engulfed and endocytosed into the cell in endosomes (vacuoles).

  3. Once inside the cell, the virus releases its viral RNA (+ssRNA)(positive single-stranded RNA) into the cytoplasm of the cell.

  4. The viral RNA (+ssRNA) can then do two things:

    1. Use the host cells ribosomes and undergo translation to make proteins.

    2. Use an enzyme call RNA dependent RNA polymerase (RNA-D-RNApol) to make more viral RNA (+ssRNA) stands.

  5. The polyproteins are then converted into the specific components of the SAR-COV-2 virus (Spike Proteins) through proteinases (enzymes)

  6. Then the structures of the virus-cell and the viral RNA copies combine to make more viruses.

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